Qianjin Lu Selected Research

Psoriasis (Pustulosis Palmaris et Plantaris)

2/2024	A multicenter, randomized, double-blinded, placebo-controlled, phase Ⅲ study evaluating the efficacy and safety of Xeligekimab (GR1501) in patients with moderate-to-severe plaque psoriasis.
1/2024	CYSLTR1 antagonist inhibits Th17 cell differentiation by regulating the NF-κB signaling for the treatment of psoriasis.
11/2023	A 2-week time-restricted feeding attenuates psoriasis-like lesions with reduced inflammatory cytokines and immunosenescence in mice.
11/2022	A randomized, double-blind phase III study to demonstrate the clinical similarity of biosimilar SCT630 to reference adalimumab in Chinese patients with moderate to severe plaque psoriasis.
1/2021	Tazarotene/Betamethasone Dipropionate Cream in Patients with Plaque Psoriasis: Results of a Prospective, Multicenter, Observational Study.
11/2020	Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
10/2020	Comparison of safety and efficacy between calcipotriol plus betamethasone dipropionate gel and calcipotriol scalp solution as long-term treatment for scalp psoriasis in Chinese patients: a national, multicentre, prospective, randomized, active-controlled phase 4 trial.
2/2020	Topical administration of nanocarrier miRNA-210 antisense ameliorates imiquimod-induced psoriasis-like dermatitis in mice.
1/2020	The pathogenic role of innate lymphoid cells in autoimmune-related and inflammatory skin diseases.
1/2019	Clinical significance and immunobiology of IL-21 in autoimmunity.

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Qianjin Lu Research Topics

Disease

63	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2024 - 06/2004
57	Autoimmune Diseases (Autoimmune Disease) 05/2024 - 05/2008
18	Psoriasis (Pustulosis Palmaris et Plantaris) 02/2024 - 07/2011
18	Neoplasms (Cancer) 07/2023 - 12/2007
16	Inflammation (Inflammations) 01/2024 - 10/2014
11	Rheumatoid Arthritis 01/2024 - 10/2015
7	Melanoma (Melanoma, Malignant) 10/2022 - 09/2017
6	Systemic Scleroderma (Systemic Sclerosis) 04/2022 - 01/2018
5	Proteinuria 05/2024 - 01/2022
5	Skin Diseases (Skin Disease) 04/2024 - 01/2020
5	Atopic Dermatitis (Atopic Eczema) 01/2024 - 12/2016
5	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 03/2013
4	Multiple Sclerosis 01/2024 - 10/2015
4	Disease Progression 01/2023 - 10/2015
4	COVID-19 01/2023 - 01/2020
4	Pemphigus (Pemphigus Vulgaris) 05/2022 - 02/2018
3	Acquired Immunodeficiency Syndrome (AIDS) 09/2023 - 10/2014
3	Sjogren's Syndrome (Sjogren Syndrome) 02/2021 - 11/2018
3	Carcinogenesis 01/2021 - 02/2011
3	Fibrosarcoma 03/2017 - 03/2009
3	Hypersensitivity (Allergy) 01/2013 - 01/2004
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2024 - 02/2017
2	Dermatitis 01/2024 - 02/2020
2	Colitis 10/2023 - 03/2013
2	Arthritis (Polyarthritis) 09/2023 - 09/2023
2	Hemorrhage 07/2023 - 01/2012
2	Lupus Nephritis 01/2023 - 01/2023
2	Bronchiolitis Obliterans Syndrome 01/2023 - 12/2022
2	Chronic Urticaria 01/2023 - 01/2022
2	Hepatocellular Carcinoma (Hepatoma) 11/2022 - 10/2018
2	Bullous Pemphigoid (Pemphigoid) 05/2022 - 01/2012
2	Fibrosis (Cirrhosis) 04/2022 - 12/2013
2	Cutaneous Lupus Erythematosus 07/2021 - 10/2009
2	Infections 01/2021 - 03/2016
2	Wilms Tumor (Wilm's Tumor) 11/2020 - 10/2018
2	Cytokine Release Syndrome 04/2020 - 01/2020
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2020 - 01/2012
2	Immune System Diseases (Immune Disorders) 11/2018 - 10/2014
2	Esophageal Squamous Cell Carcinoma 10/2011 - 12/2007
1	Hypoxia (Hypoxemia) 04/2024

Drug/Important Bio-Agent (IBA)

36	AutoantibodiesIBA 05/2024 - 05/2008
21	Biomarkers (Surrogate Marker)IBA 01/2023 - 08/2010
17	CytokinesIBA 01/2024 - 03/2013
13	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 06/2004
12	MicroRNAs (MicroRNA)IBA 10/2020 - 05/2011
12	Histones (Histone)IBA 01/2019 - 01/2010
8	Proteins (Proteins, Gene)FDA Link 07/2023 - 11/2016
7	Immunoglobulin G (IgG)IBA 01/2023 - 09/2009
7	Messenger RNA (mRNA)IBA 11/2020 - 12/2007
6	AntibodiesIBA 09/2023 - 01/2012
5	Imiquimod (Aldara)FDA LinkGeneric 01/2024 - 01/2018
5	MethyltransferasesIBA 11/2022 - 01/2010
5	RNA (Ribonucleic Acid)IBA 01/2022 - 09/2010
5	Transcription Factors (Transcription Factor)IBA 10/2021 - 09/2016
5	InterferonsIBA 02/2021 - 11/2016
4	Regulatory Factor X1IBA 10/2023 - 01/2010
4	pristane (pristan)IBA 09/2023 - 01/2018
4	Interleukin-2 (IL2)IBA 01/2023 - 01/2016
4	interleukin-21 (interleukin 21)IBA 12/2022 - 03/2017
4	AutoantigensIBA 02/2021 - 06/2016
4	ChromatinIBA 01/2019 - 01/2004
3	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 04/2024 - 03/2024
3	Therapeutic UsesIBA 09/2023 - 01/2018
3	Immunoglobulins (Immunoglobulin)IBA 07/2023 - 01/2022
3	Immunoglobulin E (IgE)IBA 01/2023 - 01/2020
3	InterleukinsIBA 01/2023 - 03/2017
3	InflammasomesIBA 01/2022 - 01/2021
3	betamethasone-17,21-dipropionate (betamethasone dipropionate)FDA LinkGeneric 01/2021 - 01/2018
3	Interferon Type IIBA 01/2021 - 11/2016
3	AllergensIBA 10/2019 - 12/2013
3	Interleukin-17 (Interleukin 17)IBA 01/2018 - 01/2015
3	Antigen-Antibody Complex (Immune Complex)IBA 07/2016 - 03/2013
2	Adenosine (Adenocard)FDA LinkGeneric 04/2024 - 01/2016
2	SolutionsIBA 01/2024 - 10/2020
2	GlucocorticoidsIBA 09/2023 - 03/2013
2	Sirtuin 1IBA 09/2023 - 07/2011
2	Immunoglobulin M (IgM)IBA 01/2023 - 01/2012
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2022 - 04/2021
2	Long Noncoding RNAIBA 12/2022 - 01/2021
2	Vitamin D FDA LinkGeneric 05/2022 - 12/2016
2	Monoclonal AntibodiesIBA 11/2021 - 02/2017
2	calcipotriene (calcipotriol)FDA LinkGeneric 10/2020 - 01/2018
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2020 - 06/2016
2	Untranslated RNA (Noncoding RNA)IBA 02/2020 - 11/2016
2	DesmogleinsIBA 12/2019 - 02/2018
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2018 - 01/2018
2	5-hydroxymethylcytosineIBA 09/2017 - 05/2016
2	ChemokinesIBA 06/2016 - 01/2015
2	AntigensIBA 01/2012 - 09/2010
2	triptolideIBA 06/2011 - 03/2009
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 06/2011 - 03/2009
1	Antinuclear AntibodiesIBA 05/2024
1	navitoclaxIBA 05/2024
1	AMP-Activated Protein KinasesIBA 04/2024
1	TOR Serine-Threonine KinasesIBA 04/2024
1	Adenosine Triphosphate (ATP)IBA 04/2024
1	Oxygen (Dioxygen)IBA 04/2024

Therapy/Procedure

25	Therapeutics 04/2024 - 02/2011
5	Fecal Microbiota Transplantation 09/2023 - 01/2022
4	Immunotherapy 01/2024 - 01/2020